When testing a multi-channel sound card it is in some applications important to make sure that the input channels are sample-synchronous. This means that the is no delay between the channels.
Note: Some data acquisition boards (that are not sound cards) is using multiplexing. Sound cards are not using this method. A multi-channel sound card consist of stereo pairs where each stereo pair contains two channels. All stereo sound cards (2 channels) should be sample-synchronous since they only have one stereo pair. But a sound card with more than two input channels should be checked.
To do this check connect output channel 1 to input channel 1. Then connect output channel 2 to input channel 3.
Perform a 3 or 4 channel measurement in WinMLS where you measure channel 1, 2 and 3. Now compare the impulse responses of channel 1 and channel 2. If they are exactly on top of each other, then the input channels are sample-synchronous.
Perform multiple measurements to make sure the result is the same for each measurement.